PRELIMINARY HPTLC INVESTIGATION OF TWO GALEOPSIS SPP. (LAMIACEAE) FROM SOUTHWEST ROMANIA FLORA

Abstract

The paper highlights the phenolic acids content of roots, aerial parts and leaves of two Galeopsis spp. (Lamiaceae) from the southwest Romania (Oltenia Region) flora, using high-performance thin-layer chromatography (HPTLC) coupled with photodensitometry. Chlorogenic acid (CGA) was identified and quantified in all 70% ethanolic extracts of Galeopsis spp. The highest CGA amount was determined in G. speciosa leaves (9.192 mg/g), followed by G. bifida leaves (9.017 mg/g), G. speciosa roots (8.283 mg/g), G. speciosa aerial parts (7.317 mg/g), G. bifida aerial parts (3.392 mg/g), and G. bifida roots (1.825 mg/g). Our research used HPTLC for the assessment of phenolic acid content, emphasizing the pharmacological potential of Galeopsis spp., mainly the antioxidant properties, which may contribute to their traditional applications in treating respiratory and inflammatory disorders.