INVESTIGATIONS ON THE DURATION OF ELIMINATION OF CERTAIN MEDICATIONS IN THE MILK OF COWS TREATED WITH MEDICATIONS

Abstract

The highest frequency is on day 1 (after treatment) after which it gradually decreases.
It should be noted that no antibiotic residues were detected in the collected milk samples prior to
treatment. Antibiotic residues may be detected in the milk of recently calved animals due to
intramammary treatments during the dry period (chronic mastitis). If the period after treatment is
less than 15 days until calving, the frequency of detecting residues in milk after calving is high. As
noted, there were two (10%) positive results, after the expiration of the waiting period, one in
intramammary treated animals and one in intramuscular treated animals on the fourth day, the first
day after the waiting period. The somatic cell count in the positive sample from intramammary
treated animals was 2850000 cells/ml and 337000 cells/ml in the sample from intramuscular
treated animals. The antibiotic residue test was influenced by the components of the milk with
mastitis. From the analysis of the treatment register, it was found that the intramuscularly treated
cow received an overdose of penicillin. This overdose resulted in a massive accumulation of
penicillin in the animal’s body resulting in an extension of the elimination period by one more day.